top of page
Xu Landén Lab
Karolinska Institute
TOOLS developed to explore our data
Kindly click the images to access the tools.
Introduction:
Human in vivo wound healing model. Full-thickness excisional wounds (4mm in diameter) are created on the skin of healthy volunteers and wound-edge tissues are collected with 6mm biopsy punches 1, 7, and 30 days later from the same donor. The time points are chosen to capture the three sequential phases of wound repair, i.e., inflammation (~3 days), proliferation (~4-21 days), and remodelling (~21days-one year).
Dataset
Tissue
Assay
Organism
Cell Number
Acute Wound
Skin
wound
10X 3' v3.1
Homo Sapiens
58,823
bioRxiv doi:
https://doi.org/10.1101/2024.08.30.609923
Dataset
Tissue
Assay
Organism
Spot Number
Donor4
Skin
wound
10X
Visum
Homo Sapiens
5,337
Donor3
Skin wound
10X
Visum
Homo Sapiens
5,558
Donor2
Skin
wound
10X
Visum
Homo Sapiens
6,411
Donor1
Skin
wound
10X
Visum
Homo Sapiens
5,609
TOOL: micro RNA & mRNA
Bulk RNA sequencing of microRNAs and mRNAs in human skin, acute wounds, and venous ulcers
TOOL: single cell Smart-seq2
Single-cell RNA sequencing of epidermal cells of human skin, acute wounds, and pressure ulcers
TOOL: circular RNA (circRNA)
Circular RNA signatures of human skin, acute wounds, and venous ulcers
bottom of page