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TOOLS developed to explore our data

Kindly click the images to access the tools.

ERC figure 1.tiff

Introduction:
Human in vivo wound healing model. Full-thickness excisional wounds (4mm in diameter) are created on the skin of healthy volunteers and wound-edge tissues are collected with 6mm biopsy punches 1, 7, and 30 days later from the same donor. The time points are chosen to capture the three sequential phases of wound repair, i.e., inflammation (~3 days), proliferation (~4-21 days), and remodelling (~21days-one year). 

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Dataset

Tissue

Assay

Organism

Cell Number

Acute Wound

Skin
wound

10X 3' v3.1

Homo Sapiens

58,823

Dataset

Tissue

Assay

Organism

Spot Number

Donor4.png

Donor4

Skin
wound

10X 
Visum

Homo Sapiens

5,337

Donor3.png

Donor3

Skin wound

10X
Visum

Homo Sapiens

5,558

Donor2.png

Donor2

Skin
wound

10X
Visum

Homo Sapiens

6,411

Donor1.png

Donor1

Skin
wound

10X
Visum

Homo Sapiens

5,609

TOOL: micro RNA & mRNA
Bulk RNA sequencing of microRNAs and mRNAs in human skin, acute wounds, and venous ulcers

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TOOL: single cell Smart-seq2
Single-cell RNA sequencing of epidermal cells of human skin, acute wounds, and pressure ulcers

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TOOL: circular RNA (circRNA)
Circular RNA signatures of human skin, acute wounds, and venous ulcers

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