-------------------- 2021 --------------------

  • Li D, Cheng S, Pei Y, Sommar P, Kärner J, Herter EK, Toma MA, Zhang L, Pham K, Cheung YT, Liu Z, Chen X, Eidsmo L, Deng Q, Landén NX. Single-cell analysis reveals MHCII expressing keratinocytes in pressure ulcers with worse healing outcomes. J Invest Dermatol. 2021 Sep 15:S0022-202X(21)02167-9. doi: 10.1016/j.jid.2021.07.176. Epub ahead of print. PMID: 34536485.

-------------------- 2020 --------------------

 

-------------------- 2019 --------------------

  • Wu J*, Li X*, Li D, Ren X, Li Y, Herter EK, Qian M, Toma MA, Wintler AM, Sérézal IG, Rollman O, Ståhle M, Wikstrom JD, Ye X, Landén NX. MicroRNA-34 family enhances wound inflammation by targeting LGR4. J Invest Dermatol. 2019 Jul 31. pii: S0022-202X(19)32680-6. doi: 10.1016/j.jid.2019.07.694. [Epub ahead of print] PubMed PMID: 31376385.

-------------------- 2018 --------------------

 

-------------------- 2017 --------------------

 

  • Li X*, Li D*, Wang A, Chu T, Lohcharoenkal W, Zheng X, Grünler J, Narayanan S, Eliasson S, Herter E, Wang Y, Ma Y, Ehrström M, Eidsmo L, Pivarcsi A, Sonkoly E, Catrina S, Ståhle M, Xu Landén N#. MicroRNA-132 with therapeutic potential in chronic wounds. J Invest Dermatol. 2017 Aug 12. pii: S0022-202X(17)32757-4. doi: 10.1016/j.jid.2017.08.003. PMID: 28807666. (*Equal contribution, #corresponding author)

 

 

 

 

 

-------------------- 2016 --------------------

  • Cheung, L., Fisher, R.M., Kuzmina, N., Li, D., Li, X., Werngren, O., Blomqvist, L., Ståhle, M., Landén, N.X.#.  (2016) Psoriasis skin inflammation-induced microRNA-26b targets NCEH1 in underlying subcutaneous adipose tissue. Journal of Investigative Dermatology 136: 640-648 PMID: 27015452 (#corresponding author)

 

  • Lohcharoenkal, W., Harada, M., Lovén, J., Meisgen, F., Landén, N.X., Zhang, L., Lapins, J., Mahapatra, K.D., Shi, H., Nissinen, L., Kähäri, V.M., Ståhle, M., Sonkoly, E., Grander, D., Arsenian-Henriksson, M., Pivarcsi, A. MicroRNA-203 inversely correlates with differentiation grade, targets c-MYC and functions as a tumor suppressor in cSCC. Journal of Investigative Dermatology 2016 Dec;136(12):2485-2494. PMID: 27452220.

 

  • Wei, Y.B., Melas,P.A., Villaescusa, J.C., Liu, J.J., Xu, N., Christiansen, S.H., Elbrønd-Bek, H., Woldbye, D.P., Wegener, G., Mathé, A.A., Lavebratt, C. MicroRNA 101b is downregulated in the prefrontal cortex of a genetic model of depression and targets the glutamate transporter SLC1A1 (EAAT3) in vitro. Int J Neuropsychopharmacol 2016 Dec 30;19(12). PMID:  27507301.

 

 

-------------------- 2015 --------------------

 

 

 

---------- Publications before Xu Landén Lab ----------

  • Checa, A., Xu, N., Sar, D.G., Haeggström, J.Z., Ståhle, M., Wheelock, C.E. (2015) Circulating levels of sphingosine-1-phosphate are elevated in severe, but not mild psoriasis and are unresponsive to anti-TNF-α treatment. Scientific Reports 2015 Jul 15; 5: 12017 PMID: 26174087

 

  • Li, J., Chen, H., Ren, J., Song, J., Zhang, F., Zhang, J., Lee, C., Li, S., Geng, Q., Cao, C., Xu, N. Effects of statin on circulating microRNAome and predicted function regulatory network in patients with unstable angina. BMC Med Genomics 8(1): 82 PMID: 25889164

 

  • Li, S., Chen, H., Ren, J., Geng, Q., Song, J., Lee, C., Cao, C., Zhang, J., Xu, N. (2014) MicroRNA-223 Inhibits Tissue Factor Expression in Vascular Endothelial Cells. Atherosclerosis 237(2): 514-20. PMID: 25463083

 

  • Kamleh, M., Snowden, S., Grapov, D., Blackburn, G., Watson, D., Xu, N., Ståhle, M., Wheelock, C. (2014) LC-MS metabolomics reveals systemic metabolic adaptations to protein requirement during keratinocyte hyperproliferation in psoriasis patients. Journal of Proteome Research 14(1): 557-66. PMID: 25361234

 

  • Wang, A#, Landén NX#, Lohcharoenkal, W., Ståhle, M., Sonkoly, E., Pivarcsi, A. (2014) MicroRNA-31 is overexpressed in cutaneous squamous cell carcinoma and regulates cell motility and colony formation ability of tumor cells. PLoS ONE Jul 28;9(7):e103206. PMID: 25068518 (#Co-first author)

 

  • Li, S., Ren, J., Xu, N., Zhang, J., Geng, Q., Cao, C., Lee, C., Song, J., Li, J., Chen, H. (2014) MicroRNA-19b functions as potential anti-thrombotic protector in patients with unstable angina by targeting tissue factor. Journal of Molecular and Cellular Cardiology Jul 3; 75C: 49-57 PMID: 24998411

 

  • Meisgen, F., Xu Landén, N., Wang, A., Réthi, B., Bovez, C., Zuccolo, M., Gueniche, A., Ståhle, M., Sonkoly, E., Breton, L., Pivarcsi, A. (2014). MiR-146a negatively regulates TLR2-induced inflammatory responses in keratinocytes.  Journal of Investigative Dermatology 134(7): 1931-40 PMID: 24670381

 

  • Hou, S, Ding H., Lv, Q, Yin, X., Song, J., Xu Landén, N., Fan, H., (2014) Therapeutic effect of intravenous infusion of perfluorocarbon emulsion on LPS-induced acute lung injury in rats. PLoS ONE Jan 28;9(1):e87826 PMID: 24489970

 

  • Meisgen, F.#, Xu Landén, N.#, Bouez, C., Zuccolo, M., Gueniche, A., Ståhle, M., Sonkoly, E., Breton, L., Pivarcsi, A. (2014) Activation of Toll-like receptors alters the microRNA expression profile of keratinocytes. Experimental Dermatology (*Co-first author) PMID: 24588688

 

  • Gastaldi, C., Bertero, T., Xu, N., Bourget-Ponzio, I., Popa, A., Cardot-Leccia, N., Michiels, J.F., Meneguzzi, G., Sonkoly, E., Pivarcsi, A., Mari, B., Barbry, P., Ponzio, G., Rezzonico, R. (2014) miR-193b/365a cluster controls progression of epidermal squamous cell carcinoma. Carcinogenesis 35(5):1110-20. PMID: 24374827

 

  • Nikamo, P., Cheuk, S., Lysell, J., Enerbäck, C., Bergh, K., Xu Landén, N., Eidsmo, L., Ståhle, M.  (2014) Genetic association of childhood psoriasis to the IL22 promoter is linked to higher promoter activity and increased IL-22 production in T cells. Journal of Investigative Dermatology 134(6):1535-41. PMID: 24390134

 

  • Wei, T.#, Xu, N.#, Meisgen, F., Ståhle, M., Sonkoly, E., Pivarcsi, A. (2013) Interleukin-8 is regulated by miR-203 at the posttranscriptional level in primary human keratinocytes. European Journal of Dermatology (* Co-first author) PMID: 23608026

 

  • Pivarcsi, A., Meisgen, F., Xu, N., Ståhle, M., Sonkoly, E. (2013) Changes in the level of serum microRNAs in psoriasispatients after anti-tumor necrosis factor-α therapy. British Journal of Dermatology 169(3): 563-70. PMID: 23600954

 

  • Ren, J., Zhang, J., Xu, N., Han G., Geng, Q., Song, J., Li, S., Zhao, J., Chen, H. (2013) Signature of Circulating MicroRNAs as Potential Biomarkers in Vulnerable Coronary Artery Disease. PLoS ONE 8(12):e80738  PMID: 24339880

 

  • Xu, N.#, Meisgen, F., Lynn, M.B., Han, G., Wang, X.J., Söderberg-Naucler, C., Ståhle, M., Pivarcsi, A., Sonkoly, E. (2012) MicroRNA-31 is overexpressed in psoriasis and modulates inflammatory cytokine and chemokine production in keratinocytes via targeting STK40. Journal of Immunology. 190(2): 678-88 (# Corresponding author) PMID: 23233723

 

  • Sääf, A., Kockum, I., Wahlgren, C.F., Xu, N., Sonkoly, E., Ståhle, M., Nordenskjöld, M., Bradley, M., Pivarcsi, A. (2012) Are BIC (miR-155) Polymorphisms Associated to Eczema Susceptibility? Acta Dermato-Venereologica. 93(3):366-7. PMID: 23047434

 

  • Xu, N#, Zhang L, Meisgen F, Harada M, Heilborn J, Homey B, Grander D, Ståhle M, Sonkoly E, Pivarcsi A. (2012) MicroRNA-125b Down-regulates Matrix Metallopeptidase 13 and Inhibits Cutaneous Squamous Cell Carcinoma Cell Proliferation, Migration and Invasion. Journal of Biological Chemistry. 287(35): 29899-908 (# Corresponding author) PMID: 22782903

 

  • Meisgen, F., Xu, N., Wei, T., Janson, P.C., Obad, S., Broom, O., Kauppinen, S. Nagy, N., Kemeny, L., Ståhle, M., Pivarcsi, A., Sonkoly, E. (2012) MiR-21 is up-regulated in psoriasis and suppresses T cell apoptosis. Experimental Dermatology. 21(4):312-4. PMID: 22417311

 

  • Sonkoly, E., Lovén, J., Xu, N., Meisgen, F., Wei, T., Brodin, P., Jaks, V., Kasper, M., Shimokawa, T., Harada, M., Heilborn, J., Hedblad, M.A., Hippe, A., Grandér, D., Homey, B., Zaphiropoulos, P.G., Arsenian-Henriksson, M., Ståhle, M., Pivarcsi, A. (2012) MicroRNA-203 Functions as a Tumor Suppressor in Basal Cell Carcinoma. Oncogenesis. Mar 12;1:e3. PMID: 23552555

 

 

 

  • Xu, N.#, Brodin, P., Wei, T., Meisgen, F., Eidsmo, L., Nagy,N., Kemeny, L., Ståhle, M., Sonkoly, E., Pivarcsi, A. (2011) MiR-125b, a microRNA down-regulated in psoriasis, modulates keratinocyte proliferation by targeting FGFR2. Journal of Investigative Dermatology 131(7): 1521-9 (#Corresponding author) PMID: 21412257

 

  • Xu, N., Akusjärvi, G. (2011). Characterization of RISC associated adenoviral small RNAs. Methods in Molecular Medicine. 721:183-98. PMID: 21431686

 

  • Sonkoly, E., Janson, P., Majuri, M., Savinko, T., Fyhrquist, N., Eidsmo, L., Xu, N., Meisgen, F., Wei, T., Bradley, M., Stenvang, J., Kauppinen, S., Alenius, H., Lauerma, A., Homey, B., Winqvist, O., Ståhle, M., Pivarcsi, A. (2010) MiR-155 is overexpressed in atopic dermatitis and modulates T cell proliferative responses by targeting CTLA-4. Journal of Allergy and Clinical Immunology 126(3): 581-9.e1-20. PMID: 20673989

 

  • Wei, T., Orfanidis, K., Xu, N., Ståhle, M., Pivarcsi, A. and Sonkoly, E. (2010) The expression of microRNA-203 during human skin morphogenesis. Experimental Dermatology 19(9): 854-6. PMID: 20698882

 

  • Xu, N., Gkountela S., Khalid S., Akusjarvi G. (2009) The 5’ ends heterogeneity of adenovirus virus-associated RNAI contributes to the asymmetric guide strand incorporation into the RNA-induced silencing complex. Nucleic Acids Research. 37(20): 6950-9 PMID: 19755500

 

  • Xu, N., Segerman B., Zhou X., Akusjärvi, G. (2007) Adenovirus virus-associated RNAII-derived small RNAs are efficiently incorporated into the RNA-induced silencing complex and associate with polyribosomes. Journal of virology. 81, 10540-9 PMID: 17652395

 

  • Andersson, G., Xu, N. and Akusjärvi, G. (2007). In vitro methods to study RNA interference during an adenovirus infection. Methods in Molecular Medicine. 131, 47-61 PMID: 17656774

 

  • Andersson, M. G., Haasnoot, P. C. J., Xu, N., Berenjian, S., Berkhout, B. and Akusjärvi, G. (2005) Suppression of RNA interference by adenovirus VA RNA. Journal of virology. 79, 9556-9565. PMID: 16014917