Molecular Wound Healing Lab
Karolinska Institute
---------- Cover article ----------
Liu Z, Bian X, Luo L, Björklund ÅK, Li L, Zhang L, Chen Y, Guo L, Gao J, Cao C, Wang J, He W, Xiao Y, Zhu L, Annusver K, Gopee NH, Basurto-Lozada D, Horsfall D, Bennett CL, Kasper M, Haniffa M, Sommar P, Li D, Xu Landén N. Spatiotemporal single-cell roadmap of human skin wound healing, Cell Stem Cell, 2025. PMID: 39729995
On the cover: In this image Liu et al. portray a dynamic cellular relay race in human skin wound healing, where keratinocytes, macrophages, and fibroblasts cooperatively heal wounds. Inflammatory macrophages clear cell debris immediately after injury and pass signals to fibroblasts at the proliferative stage, which remodel the extracellular matrix, setting the path for keratinocytes to migrate and close the wound. This cooperation highlights the vital interplay of cells in driving reepithelialization and repairing skin wound healing.
Niu G, Toma MA, Geara J, Bian X, Chen Y, Luo L, Wang Q, Xiao Y, Vij M, Piipponen M, Liu Z, Oasa S, Zhang L, Schlesinger D, Végvári Á, Li D, Wang A, Vukojević V, Elsässer SJ, Sommar P, Xu Landén N. Collaborative Duality of CircGLIS3(2) RNA and Protein in human Wound Repair, Advanced Science, 2025, PMID: 40279507
CircRNA in Wound Healing
The image depicts CircGLIS3(2) as a powerful figure driving wound healing by uniting a mountain with chains. Its RNA stabilizes PCOLCE (green) to activate fibroblasts, while its protein interacts with BTF3 (orange) to boost proliferation. These dual actions accelerate repair.
--------------------- 2025 --------------------
73. Shang M-M, Liu Z#, Knezevic B#, Möller Westerberg C, Panda SK, Fang H, Xu Landén N, Sundström M, Knight JC, Berg L. Combining computational target prioritization and a B cell maturation assay for target evaluation studies in systemic lupus erythematosus, Translational Research, 2025, PMID: 40934967
72. Niu G, Geara J, Chen Y, Xiao Y, Liu Z, Sommar P, Wang A, Zheng X, Xu Landén N. Mitochondrial CircRNA CircMT-RNR2 Safeguards Antioxidant Defense to Support Fibroblast Functions in Wound Repair, 2025, bioRxiv, doi: https://doi.org/10.1101/2025.09.03.673954
71. Chen Y, El Mahi Y, Aubin F, Saas P, Xu Landén N, Gallais Sérézal I. Tracking molecular predictors of relapse in psoriasis upon cessation of biologics: identification of highly relevant markers, Journal of Investigative Dermatology, 2025, PMID: 40738244
70. Niu G, Toma MA, Geara J, Bian X, Chen Y, Luo L, Wang Q, Xiao Y, Vij M, Piipponen M, Liu Z, Oasa S, Zhang L, Schlesinger D, Végvári Á, Li D, Wang A, Vukojević V, Elsässer SJ, Sommar P, Xu Landén N. Collaborative Duality of CircGLIS3(2) RNA and Protein in human Wound Repair, Advanced Science, 2025, PMID: 402795
--------------------- 2024 --------------------
69. Liu Z, Bian X, Luo L, Björklund ÅK, Li L, Zhang L, Chen Y, Guo L, Gao J, Cao C, Wang J, He W, Xiao Y, Zhu L, Annusver K, Gopee NH, Basurto-Lozada D, Horsfall D, Bennett CL, Kasper M, Haniffa M, Sommar P, Li D, Xu Landén N. Spatiotemporal single-cell roadmap of human skin wound healing, Cell Stem Cell, 2024, PMID: 39729995
68. Bian X, Piipponen M, Liu Z, Luo L, Geara J, Chen Y, Sangsuwan T, Maselli M, Diaz C, Bain CA, Eenjes E, Genander M, Crichton M, Cash JL, Archambault L, Haghdoost S, Fradette J, Sommar P, Halle M, Xu Landén N. Epigenetic memory of radiotherapy in dermal fibroblasts impairs wound repair capacity in cancer survivors. Nature Communications, 2024. PMID: 39468077
67. Li D, Liu Z, Zhang L, Bian X, Wu J, Li L, Chen Y, Luo L, Pan L, Kong L, Xiao Y, Wang J, Zhang X, Wang W, Toma M, Piipponen M, Sommar P, Xu Landén N. The lncRNA SNHG26 drives the inflammatory-to-proliferative state transition of keratinocyte progenitor cells during wound healing. Nature Communications, 2024,
PMID: 39366968 [KI news: https://news.ki.se/key-molecule-in-wound-healing-identified]
66. Wang Q, Niu G, Liu Z, Toma MA, Geara J, Bian X, Zhang L, Piipponen M, Li D, Wang A, Sommar P, Xu Landén N. Circular RNA circASH1L(4,5) protects microRNA-129-5p from target-directed microRNA degradation in human skin wound healing. British Journal of Dermatology, 2025 PMID: 39422230
65. Xiao Y†, Zhang C†, Liu X, Yang Y, Xu Landén N, Zhang Z* and Li D*. Single-cell profiling and functional screening reveal crucial roles for lncRNAs in the epidermal re-epithelialization of human acute wounds. Frontiers in Surgery. 2024, PMID: 38468869
--------------------- 2023 --------------------
64. Almet AA, Yuan H, Annusver K, Ramos R, Liu Y, Wiedemann J, Sorkin DH, Xu Landén N, Sonkoly E, Haniffa M, Nie Q, Lichtenberger BM, Luecken MD, Andersen B, Tsoi LC, Watt FM, Gudjonsson JE, Plikus MV, Kasper M. A Roadmap for a Consensus Human Skin Cell Atlas and Single-Cell Data Standardization. Journal of Investigative Dermatology. 2023, PMID: 37612031.
63. Zhang L, Piipponen M, Liu Z, Li D, Bian X, Liu G, Geara J, Toma M, Sommar P & Xu Landén N. Human skin specific long noncoding RNA HOXC13-AS regulates epidermal differentiation by interfering with Golgi-ER retrograde transport. Cell Death & Differentiation, 2023, PMID: 36869179
[KI news: https://news.ki.se/novel-human-specific-mechanism-of-the-skin-barrier-regeneration]
--------------------- 2022 --------------------
62. Liu Z*, Zhang L*, Toma MA, Li D, Bian X, Pastar I, Tomic-Canic M, Sommar P, Xu Landén N. Integrative small and long RNA omics analysis of human healing and nonhealing wounds discovers cooperating microRNAs as therapeutic targets. eLife, 2022, PMID: 35942686
[KI news: https://news.ki.se/new-findings-on-potential-targets-for-treating-venous-ulcers.]
61. Konieczny P#, Xing Y#, Sidhu I, Subudhi I, Mansfield KP, Hsieh B, Biancur DE, Larsen SB, Cammer M, Li D, Xu Landén N, Loomis C, Heguy A, Tikhonova AN, Tsirigos A, Naik S. Interleukin-17 governs hypoxic adaptation of injured epithelium. Science, 2022. PMID: 35709248
60. Toma MA*, Liu Z*†, Wang Q, Zhang L, Li D, Sommar P, Xu Landén N. Circular RNA signatures of human healing and non-healing wounds. Journal of Investigative Dermatology, 2022. PMID: 35429518
59. Li D*, Niu G*, Xu Landén N. Beyond the Code: Noncoding RNAs in Skin Wound Healing. Cold Spring Harb Perspect Biol. 2022 Feb 23:a041230. (*Co-first author)
--------------------- 2021 --------------------
58. Li X, Ponandai-Srinivasan S, Nandakumar KS, Fabre S, Xu Landén N, Mavon A, Khmaladze I. Targeting microRNA for improved skin health. Health Sci Rep. 2021 Oct 12;4(4):e374. doi: 10.1002/hsr2.374. PMID: 34667882; PMCID: PMC8506131.
57. Li D, Cheng S, Pei Y, Sommar P, Kärner J, Herter EK, Toma MA, Zhang L, Pham K, Cheung YT, Liu Z, Chen X, Eidsmo L, Deng Q, Landén NX. Single-cell analysis reveals MHCII expressing keratinocytes in pressure ulcers with worse healing outcomes. Journal of Investigative Dermatology, 2021. PMID: 34536485.
56. Li J, Zhang X, Yang M, Yang H, Xu N, Fan X, Liu G, Jiang X, Fan J, Zhang L, Zhang H, Zhou Y, Li R, Gao S, Jin J, Jin Z, Zheng J, Tu Q, Ren J. DNA methylome profiling reveals epigenetic regulation of lipoprotein-associated phospholipase A in human vulnerable atherosclerotic plaque. Clin Epigenetics. 2021 Aug 21;13(1):161. doi: 10.1186/s13148-021-01152-z. PMID: 34419168; PMCID: PMC8379831.
--------------------- 2020 --------------------
55. Piipponen M, Li D, Xu Landén N.# The immune functions of keratinocytes in skin wound healing. Int. J. Mol. Sci. 2020, 21, 8790. (Review)
54. Narayanan S, Angelstig S E, Xu C, Grünler J, Zhao A, Zhu W, Xu Landén N, Ståhle M, Zhang J, Ivan M, Maltesen R G, Botusan I R, Ekberg N R, Zheng X, Catrina S-B. HypoxamiR-210 accelerates wound healing in diabetic mice by improving cellular metabolism. Commun Biol 3, 768 (2020).
53. Li D, Peng H, Qu L, Sommar P, Wang A, Chu T, Li X, Bi X, Liu Q, Sérézal IG, Rollman O, Lohcharoenkal W, Zheng X, Angelstig SE, Grünler J, Pivarcsi A, Sonkoly E, Catrina S-B, Xiao C, Ståhle M, Mi Q-S, Zhou L#, Xu Landén N. miR-19a/b and miR-20a promote wound healing by regulating the inflammatory response of keratinocytes. Journal of Investigative Dermatology, Accepted on June 29th, 2020.
52. Li X, Landén NX. Evaluation of MicroRNA Therapeutic Potential Using the Mouse In Vivo and Human Ex Vivo Wound Models. Methods in Molecular Biology, 2020;2193:67-75. PMID: 32808259.
51. Wu J, Landén NX. Investigation of Skin Wound Healing Using a Mouse Model. Methods Mol Biol. 2020;2154:239‐247. doi:10.1007/978-1-0716-0648-3_20.
--------------------- 2019 --------------------
50. Wang A*,†, Toma MA†, Ma J, Li D, Vij M, Chu T, Wang J, Li X, Xu Landén N*. Circular RNA hsa_circ_0084443 is upregulated in diabetic foot ulcer and modulates keratinocyte migration and proliferation. Advances in Wound Care (New Rochelle). 2019. PMID: 32117579
49. Wu J*, Li X*, Li D, Ren X, Li Y, Herter EK, Qian M, Toma M-A, Wintler A-M, Gallais Sérézal I, Rollman O, Ståhle M, Wikstrom JD, Ye X, Xu Landén N. MicroRNA-34 family enhances wound inflammation by targeting LGR4. Journal of Investigative Dermatology, 2019. PubMed PMID: 31376385.
48. Srivastava A, Meisgen F, Pasquali L, Munkhammar S, Xia P, Ståhle M, Xu Landén N, Pivarcsi A, Sonkoly E. Next generation sequencing identifies the keratinocyte-specific miRNA signature of psoriasis. Journal of Investigative Dermatology, 2019. PMID: 31207228.
47. Li D, Kular L, Vij M, Herter EK, Li X, Wang A, Chu T, Toma M-A, Zhang L, Liapi E, Mota A, Blomqvist L, Gallais Sérézal I, Rollman O, Wikstrom JD, Bienko M, Berglund D, Ståhle M, Sommar P, Jagodic M, Xu Landén N. Human skin long noncoding RNA WAKMAR1 regulates wound healing by enhancing keratinocyte migration. Proc Natl Acad Sci U S A, 2019. PMID: 31019085.
46. Pasquali, L. Srivastava, A. Meisgen, F. Das Mahapatra, K. Xia, P. Xu Landén, N. Pivarcsi, A. Sonkoly, E. The Keratinocyte Transcriptome in Psoriasis: Pathways Related to Immune Responses, Cell Cycle and Keratinization. Acta Derm Venereol, 2019. PMID: 30320872.
-------------------- 2018 --------------------
45. Herter EK, Li D, Toma MA, Vij M, Li X, Visscher D, Wang A, Chu T, Sommar P, Blomqvist L, Berglund D, Ståhle M, Wikstrom JD, Xu Landén N#. WAKMAR2, A Long Noncoding RNA Downregulated in Human Chronic Wounds, Modulates Keratinocyte Motility and Production of Inflammatory Chemokines, Journal of Investigative Dermatology, 2018. PMID: 30594489
44. Lohcharoenkal W, Das Mahapatra K, Pasquali L, Crudden C, Kular L, Akkaya Ulum YZ, Zhang L, Xu Landén N, Girnita L, Jagodic M, Ståhle M, Sonkoly E, Pivarcsi A. Genome-Wide Screen for MicroRNAs Reveals a Role for miR-203 in Melanoma Metastasis. Journal of Investigative Dermatology, 2018. PMID: 29104160.
43. Gallais Sérézal I, Classon C, Cheuk S, Barrientos-Somarribas M, Wadman E, Martini E, Chang D, Xu Landén N, Ehrström M, Nylén S, Eidsmo L. Resident T Cells in Resolved Psoriasis Steer Tissue Responses that Stratify Clinical Outcome. Journal of Investigative Dermatology. PMID: 29510191.
-------------------- 2017 --------------------
42. Li X*, Li D*, Wang A, Chu T, Lohcharoenkal W, Zheng X, Grünler J, Narayanan S, Eliasson S, Herter EK, Wang Y, Ma Y, Ehrström M, Eidsmo L, Kasper M, Pivarcsi A, Sonkoly E, Catrina S-B, Ståhle M, Xu Landén N.. MicroRNA-132 with therapeutic potential in chronic wounds. Journal of Investigative Dermatology, 2017. PMID: 28807666.
41. Li X, Li D, Wikstrom JD, Pivarcsi A, Sonkoly E, Ståhle M & Xu Landén N. MicroRNA-132 promotes fibroblast migration via regulating RAS p21 protein activator 1 in skin wound healing. Scientific Reports, 2017. PMID: 28798331.
40. Li D & Xu Landén N. MicroRNAs in skin wound healing. European Journal of Dermatology, 2017. PMID: 28690209 (Review)
39. Herter EK, Xu Landén N. Non-Coding RNAs: New Players in Skin Wound Healing. Advances in Wound Care (New Rochelle), 2017. PMID: 28289554 (Review)
38. Wei, T., Folkersen, L., Biskup, E., Xu, N., Manfe, V., Niazi, O., Gniadecki, R. Ubiquitin-specific peptidase 2 as a potential link between microRNA-125b and psoriasis. British Journal of Dermatology, 2017. PMID: 27479112
37. Srivastava A, Nikamo P, Lohcharoenkal W, Li D, Meisgen F, Xu Landén N, Ståhle M, Pivarcsi A, Sonkoly E. MicroRNA-146a suppresses IL-17-mediated skin inflammation and is genetically associated with psoriasis. Journal of Allergy and Clinical Immunology, 2017. PMID: 27568078.
-------------------- 2016 --------------------
36. Cheung L, Fisher RM, Kuzmina N, Li D, Li X, Werngren O, Blomqvist L, Ståhle M, Xu Landén N. Psoriasis skin inflammation-induced microRNA-26b targets NCEH1 in underlying subcutaneous adipose tissue. Journal of Investigative Dermatology, 2016. PMID: 27015452
35. Lohcharoenkal W, Harada M, Lovén J, Meisgen F, Xu Landén N, Zhang L, Lapins J, Das Mahapatra K, Shi H, Nissinen L, Kähäri V-M, Ståhle M, Sonkoly E, Grandér D, Arsenian-Henriksson M, Pivarcsi A. MicroRNA-203 inversely correlates with differentiation grade, targets c-MYC and functions as a tumor suppressor in cSCC. Journal of Investigative Dermatology, 2016. PMID: 27452220.
34. Wei YB, Melas PA, Villaescusa JC, Liu JJ, Xu N, Christiansen SH, Elbrønd-Bek H, Woldbye DPD, Wegener G, Mathé AA, Lavebratt C. MicroRNA 101b is downregulated in the prefrontal cortex of a genetic model of depression and targets the glutamate transporter SLC1A1 (EAAT3) in vitro. International Journal of Neuropsychopharmacology, 2016. PMID: 27507301.
33. Xu Landén N#, Li D, Ståhle M. Transition from inflammation to proliferation: a critical step during wound healing. Cellular and Molecular Life Sciences, 2016. PMID: 27180275
--------------------- 2015 --------------------
32. Li D*, Wang A*, Liu X, Meisgen F, Grünler J, Botusan IR, Narayanan S, Erikci E, Li X, Blomqvist L, Du L, Pivarcsi A, Sonkoly E, Chowdhury K, Catrina SB, Ståhle M and Xu Landén N. MicroRNA-132 enhances transition from inflammation to proliferation during wound healing. Journal of Clinical Investigation, 2015. PMID: 26121747
31. Li D, Li XI, Wang A, Meisgen F, Pivarcsi A, Sonkoly E, Ståhle M, Xu Landén N. MicroRNA-31 promotes skin wound healing by enhancing keratinocyte proliferation and migration. Journal of Investigative Dermatology, 2015. PMID: 25685928
30. Wang A, Xu Landén N. New insights into CD4+ T cells and their signature cytokines in atopic dermatitis. IUBMB Life, 2015. PMID: 26178387 (Review)
--------------------- Publications before Xu Landén Lab --------------------
29. Checa, A., Xu, N., Sar, D.G., Haeggström, J.Z., Ståhle, M., Wheelock, C.E. (2015) Circulating levels of sphingosine-1-phosphate are elevated in severe, but not mild psoriasis and are unresponsive to anti-TNF-α treatment. Scientific Reports 2015 Jul 15; 5: 12017 PMID: 26174087
28. Li, J., Chen, H., Ren, J., Song, J., Zhang, F., Zhang, J., Lee, C., Li, S., Geng, Q., Cao, C., Xu, N. Effects of statin on circulating microRNAome and predicted function regulatory network in patients with unstable angina. BMC Med Genomics 8(1): 82 PMID: 25889164
27. Li, S., Chen, H., Ren, J., Geng, Q., Song, J., Lee, C., Cao, C., Zhang, J., Xu, N. (2014) MicroRNA-223 Inhibits Tissue Factor Expression in Vascular Endothelial Cells. Atherosclerosis 237(2): 514-20. PMID: 25463083
26. Kamleh, M., Snowden, S., Grapov, D., Blackburn, G., Watson, D., Xu, N., Ståhle, M., Wheelock, C. (2014) LC-MS metabolomics reveals systemic metabolic adaptations to protein requirement during keratinocyte hyperproliferation in psoriasis patients. Journal of Proteome Research 14(1): 557-66. PMID: 25361234
25. Wang, A#, Landén NX#, Lohcharoenkal, W., Ståhle, M., Sonkoly, E., Pivarcsi, A. (2014) MicroRNA-31 is overexpressed in cutaneous squamous cell carcinoma and regulates cell motility and colony formation ability of tumor cells. PLoS ONE Jul 28;9(7):e103206. PMID: 25068518 (#Co-first author)
24. Li, S., Ren, J., Xu, N., Zhang, J., Geng, Q., Cao, C., Lee, C., Song, J., Li, J., Chen, H. (2014) MicroRNA-19b functions as potential anti-thrombotic protector in patients with unstable angina by targeting tissue factor. Journal of Molecular and Cellular Cardiology Jul 3; 75C: 49-57 PMID: 24998411
23. Meisgen, F., Xu Landén, N., Wang, A., Réthi, B., Bovez, C., Zuccolo, M., Gueniche, A., Ståhle, M., Sonkoly, E., Breton, L., Pivarcsi, A. (2014). MiR-146a negatively regulates TLR2-induced inflammatory responses in keratinocytes. Journal of Investigative Dermatology 134(7): 1931-40 PMID: 24670381
22. Hou, S, Ding H., Lv, Q, Yin, X., Song, J., Xu Landén, N., Fan, H., (2014) Therapeutic effect of intravenous infusion of perfluorocarbon emulsion on LPS-induced acute lung injury in rats. PLoS ONE Jan 28;9(1):e87826 PMID: 24489970
21. Meisgen, F.#, Xu Landén, N.#, Bouez, C., Zuccolo, M., Gueniche, A., Ståhle, M., Sonkoly, E., Breton, L., Pivarcsi, A. (2014) Activation of Toll-like receptors alters the microRNA expression profile of keratinocytes. Experimental Dermatology (*Co-first author) PMID: 24588688
20. Gastaldi, C., Bertero, T., Xu, N., Bourget-Ponzio, I., Popa, A., Cardot-Leccia, N., Michiels, J.F., Meneguzzi, G., Sonkoly, E., Pivarcsi, A., Mari, B., Barbry, P., Ponzio, G., Rezzonico, R. (2014) miR-193b/365a cluster controls progression of epidermal squamous cell carcinoma. Carcinogenesis 35(5):1110-20. PMID: 24374827
19. Nikamo, P., Cheuk, S., Lysell, J., Enerbäck, C., Bergh, K., Xu Landén, N., Eidsmo, L., Ståhle, M. (2014) Genetic association of childhood psoriasis to the IL22 promoter is linked to higher promoter activity and increased IL-22 production in T cells. Journal of Investigative Dermatology 134(6):1535-41. PMID: 24390134
18. Wei, T.#, Xu, N.#, Meisgen, F., Ståhle, M., Sonkoly, E., Pivarcsi, A. (2013) Interleukin-8 is regulated by miR-203 at the posttranscriptional level in primary human keratinocytes. European Journal of Dermatology (* Co-first author) PMID: 23608026
17. Pivarcsi, A., Meisgen, F., Xu, N., Ståhle, M., Sonkoly, E. (2013) Changes in the level of serum microRNAs in psoriasispatients after anti-tumor necrosis factor-α therapy. British Journal of Dermatology 169(3): 563-70. PMID: 23600954
16. Ren, J., Zhang, J., Xu, N., Han G., Geng, Q., Song, J., Li, S., Zhao, J., Chen, H. (2013) Signature of Circulating MicroRNAs as Potential Biomarkers in Vulnerable Coronary Artery Disease. PLoS ONE 8(12):e80738 PMID: 24339880
15. Xu, N.#, Meisgen, F., Lynn, M.B., Han, G., Wang, X.J., Söderberg-Naucler, C., Ståhle, M., Pivarcsi, A., Sonkoly, E. (2012) MicroRNA-31 is overexpressed in psoriasis and modulates inflammatory cytokine and chemokine production in keratinocytes via targeting STK40. Journal of Immunology. 190(2): 678-88 (# Corresponding author) PMID: 23233723
14. Sääf, A., Kockum, I., Wahlgren, C.F., Xu, N., Sonkoly, E., Ståhle, M., Nordenskjöld, M., Bradley, M., Pivarcsi, A. (2012) Are BIC (miR-155) Polymorphisms Associated to Eczema Susceptibility? Acta Dermato-Venereologica. 93(3):366-7. PMID: 23047434
13. Xu, N#, Zhang L, Meisgen F, Harada M, Heilborn J, Homey B, Grander D, Ståhle M, Sonkoly E, Pivarcsi A. (2012) MicroRNA-125b Down-regulates Matrix Metallopeptidase 13 and Inhibits Cutaneous Squamous Cell Carcinoma Cell Proliferation, Migration and Invasion. Journal of Biological Chemistry. 287(35): 29899-908 (# Corresponding author) PMID: 22782903
12. Meisgen, F., Xu, N., Wei, T., Janson, P.C., Obad, S., Broom, O., Kauppinen, S. Nagy, N., Kemeny, L., Ståhle, M., Pivarcsi, A., Sonkoly, E. (2012) MiR-21 is up-regulated in psoriasis and suppresses T cell apoptosis. Experimental Dermatology. 21(4):312-4. PMID: 22417311
11. Sonkoly, E., Lovén, J., Xu, N., Meisgen, F., Wei, T., Brodin, P., Jaks, V., Kasper, M., Shimokawa, T., Harada, M., Heilborn, J., Hedblad, M.A., Hippe, A., Grandér, D., Homey, B., Zaphiropoulos, P.G., Arsenian-Henriksson, M., Ståhle, M., Pivarcsi, A. (2012) MicroRNA-203 Functions as a Tumor Suppressor in Basal Cell Carcinoma. Oncogenesis. Mar 12;1:e3. PMID: 23552555
10. Tang, H.M., Chen, H., Zhang, J. Ren, J.Y., Xu, N. Application of next generation sequencing in microRNA detection. HEREDITAS (Beijing), 2012. PMID: 22698751
9. Ren, J., Xu, N., Han, G., Chen, H. MicroRNAs in the Pathogenesis of Atherosclerosis. Chinese Journal of Biochemistry and Molecular Biology, 2011.
8. Xu, N.#, Brodin, P., Wei, T., Meisgen, F., Eidsmo, L., Nagy,N., Kemeny, L., Ståhle, M., Sonkoly, E., Pivarcsi, A. MiR-125b, a microRNA down-regulated in psoriasis, modulates keratinocyte proliferation by targeting FGFR2. Journal of Investigative Dermatology, 2011. (#Corresponding author) PMID: 21412257
7. Xu, N., Akusjärvi, G. Characterization of RISC associated adenoviral small RNAs. Methods in Molecular Medicine, 2011. PMID: 21431686
6. Sonkoly, E., Janson, P., Majuri, M., Savinko, T., Fyhrquist, N., Eidsmo, L., Xu, N., Meisgen, F., Wei, T., Bradley, M., Stenvang, J., Kauppinen, S., Alenius, H., Lauerma, A., Homey, B., Winqvist, O., Ståhle, M., Pivarcsi, A. MiR-155 is overexpressed in atopic dermatitis and modulates T cell proliferative responses by targeting CTLA-4. Journal of Allergy and Clinical Immunology, 2010. PMID: 20673989
5. Wei, T., Orfanidis, K., Xu, N., Ståhle, M., Pivarcsi, A. and Sonkoly, E. The expression of microRNA-203 during human skin morphogenesis. Experimental Dermatology, 2010. PMID: 20698882
4. Xu, N., Gkountela S., Khalid S., Akusjarvi G. The 5’ ends heterogeneity of adenovirus virus-associated RNAI contributes to the asymmetric guide strand incorporation into the RNA-induced silencing complex. Nucleic Acids Research, 2009. PMID: 19755500
3. Xu, N., Segerman B., Zhou X., Akusjärvi, G. Adenovirus virus-associated RNAII-derived small RNAs are efficiently incorporated into the RNA-induced silencing complex and associate with polyribosomes. Journal of Virology, 2007. PMID: 17652395
2. Andersson, G., Xu, N. and Akusjärvi, G. In vitro methods to study RNA interference during an adenovirus infection. Methods in Molecular Medicine, 2007. PMID: 17656774
1. Andersson, M. G., Haasnoot, P. C. J., Xu, N., Berenjian, S., Berkhout, B. and Akusjärvi, G. Suppression of RNA interference by adenovirus VA RNA. Journal of Virology, 2005. PMID: 16014917